Get 3-in-1 Sexual Health Medication
Connect with licensed providers who treat sexual health concerns through our secure telehealth platform. A provider can evaluate whether a compounded prescription combining tadalafil with oxytocin and PT-141 is appropriate for you, or whether another option fits better. Get personalized guidance on prescription treatment options from the privacy of your home.
FDA status: The 3-in-1 is compounded by a 503A pharmacy and is not FDA-approved. Tadalafil alone is FDA-approved for ED and BPH; PT-141 in men and oxytocin for sexual health are off-label. Compounded drugs are not reviewed by the FDA for safety or effectiveness.
How to Connect to a Sexual Health Doctor Online with Heally?
Heally makes it easy to connect with a licensed sexual health doctor from the comfort and privacy of your home. Our sexual health online platform provides a straightforward, discreet way to discuss your concerns and explore treatment options. Here's how our sexual health service works:
Schedule Your Free Consultation
Begin by booking a complimentary consultation through our secure platform. Choose a convenient time that works for you. You'll provide basic information about your health history and concerns, helping our providers understand your goals and determine which treatment options might be appropriate for your needs.
Meet with a Healthcare Professional
Connect with a qualified sexual health provider through our secure video platform at your scheduled time. During this private consultation, you'll discuss your health goals and treatment options, including the compounded 3-in-1 medication. Your provider will answer any questions and determine the most appropriate treatment plan for your specific situation.
Receive Your Personalized Treatment Plan
If appropriate, your provider will create a customized treatment plan and prescription. Our partner pharmacy will prepare your medication and ship it directly to your home in discreet packaging. The entire process is confidential, ensuring your privacy from consultation to delivery.
Erectile dysfunction treatment: what to know about the 3-in-1 compounded blend
What to know before starting the 3-in-1: how each ingredient works, its FDA status, who should not use it, and how your provider monitors you. The 3-in-1 is a compounded combination of tadalafil, oxytocin and PT-141 (bremelanotide) made by a 503A pharmacy. It is not FDA-approved, and its safety and effectiveness have not been evaluated by the FDA. Tadalafil alone is FDA-approved for erectile dysfunction and BPH. Bremelanotide is FDA-approved only as Vyleesi, an injection for premenopausal women with acquired generalized HSDD; use in men or for ED is off-label. Oxytocin is not FDA-approved for sexual health.
FDA status
The 3-in-1 combination is compounded by a 503A pharmacy and is not FDA-approved. The FDA has not studied or approved this combination for safety or effectiveness. Compounded drugs are not reviewed by the FDA for safety or effectiveness.
Tadalafil
Tadalafil (the active ingredient in Cialis) is a PDE5 inhibitor. It relaxes blood vessels and increases blood flow to the penis when sexual stimulation occurs. Tadalafil alone is FDA-approved for erectile dysfunction and BPH. Heally does not dispense branded Cialis; tadalafil in the 3-in-1 is compounded.
Oxytocin
Oxytocin, sometimes called the "bonding hormone," is a hormone that acts on receptors in the brain and body. Oxytocin's role in intimacy is being studied; it is not FDA-approved for sexual health. If prescribed, your provider sets and monitors the dose.
PT-141
PT-141 (bremelanotide) acts on melanocortin receptors in the brain rather than on blood vessels. PT-141 (bremelanotide) is FDA-approved only as Vyleesi for premenopausal women with HSDD. Use in men is off-label and has limited evidence. It can cause nausea, flushing and a temporary rise in blood pressure.
Provider evaluation
Your provider reviews your heart health, blood pressure and medications. The 3-in-1 is not for you if you take nitrates or riociguat, have uncontrolled blood pressure, or have been told sexual activity is unsafe for your heart. Your provider decides whether it is appropriate.
Monitoring
Your provider checks in after you start to review how you tolerate it and any side effects, then decides whether to continue, adjust or stop. Response varies, and the combination has not been evaluated by the FDA.
Why Choose Heally for Sexual Health Care Online?
Heally is a telehealth platform that connects you with licensed providers in a discreet and professional environment. Our platform makes it easy to talk to a sexual health doctor online from the privacy of your home. Whether you have questions about FDA-approved or compounded prescription medications, our providers offer care tailored to your needs.
Convenient Access
Expert Medical Guidance
Comprehensive Treatment Options
Private and Discreet Care
Ongoing Support
and a patient-first approach.
Book Sex Health Prescription Online
Getting started with a sexual health doctor online has never been easier through our secure telehealth platform. We offer two types of visits to help you access prescription treatment when appropriate:
Sexual Health FAQ
-
When should I consider using sexual health medications?
You might consider sexual health medications if you're experiencing challenges with intimate function that affect your quality of life. Common reasons include difficulty maintaining erections, decreased libido, or concerns about sexual performance. However, it's essential to consult with a healthcare provider who can evaluate your specific situation and determine if medication is appropriate.
-
Should I use Tadalafil, Oxytocin and
PT-141 at the same time?This combination is compounded and has not been studied or approved by the FDA as a combination. Your provider decides whether it is appropriate for you. Never combine these medications on your own without medical supervision.
-
How do 3-in-1 sexual health medications work?
Each component in the 3-in-1 medication works differently:
- Tadalafil is a PDE5 inhibitor that increases blood flow; alone it is FDA-approved for ED and BPH
- Oxytocin acts on receptors in the brain and body; its role in intimacy is being studied and it is not FDA-approved for sexual health
- PT-141 (bremelanotide) acts on melanocortin receptors in the brain; it is FDA-approved only as Vyleesi for premenopausal women with HSDD, and use in men is off-label. The combination is compounded and has not been evaluated by the FDA.
-
What are the most common side effects
of sexual health medications?Potential side effects may include:
- Headache
- Facial flushing
- Nasal congestion
- Mild digestive issues
- Nausea, flushing and a temporary rise in blood pressure (PT-141)
- Do not use with nitrates or riociguat (risk of a dangerous drop in blood pressure). Get emergency care for an erection lasting more than 4 hours or sudden vision or hearing loss. Report any unusual reactions to your provider immediately.
-
How can I obtain a prescription for sexual health medication?
You can obtain a prescription through Heally by:
- Scheduling a free initial consultation
- Meeting with a licensed healthcare provider
- Discussing your health history and concerns
- If appropriate, receiving a prescription during a follow-up treatment visit The entire process is confidential and can be completed online.
-
When can I expect to see results after starting Tadalafil, Oxytocin and PT-141?
Response varies, and the compounded combination has not been evaluated by the FDA. Your provider checks in after you start to review side effects and how you are doing, then decides whether to continue, adjust or stop treatment.
-
How do I find a specialist to consult about
sexual health medications?Through Heally's platform, you can connect with qualified healthcare providers who specialize in sexual health. Our providers are licensed professionals with experience in prescribing and managing sexual health medications. The consultation process is discrete, professional, and conducted entirely online.
-
Can sexual health medications be used in combination with other treatments?
The possibility of combining sexual health medications with other treatments depends on various factors, including your medical history and current medications. Always inform your healthcare provider about any medications, supplements, or treatments you're using. They can determine what combinations are safe and appropriate for your situation.
With more than 30 years of physician practice in the Obstetrics and Gynecology specialty, Dr. Niles is recognized as a leading authority on the delivery of quality medical care. She has a well-established and respected history of worldwide medical collaboration, research, philanthropy, and distinguished leadership.
The 3-in-1 is a compounded combination of tadalafil, oxytocin and PT-141 (bremelanotide) made by a 503A pharmacy. It is not FDA-approved, and its safety and effectiveness have not been evaluated by the FDA. Tadalafil alone is FDA-approved for erectile dysfunction and BPH. Bremelanotide is FDA-approved only as Vyleesi, an injection for premenopausal women with acquired generalized HSDD; use in men or for ED is off-label. Oxytocin is not FDA-approved for sexual health. Compounded drugs are not FDA-approved and are not reviewed by the FDA for safety or effectiveness. Do not use with nitrates or riociguat. This page is for general educational purposes only and is not medical advice.
Data Last Updated 10/05/2026