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Longevity and Anti-Aging Medicine Online

Talk online with a licensed physician about longevity medications, their FDA status and risks. If a prescription is appropriate, it ships to your door.

FDA status: No medication is FDA-approved to slow aging. Rapamycin, metformin and methylene blue have other FDA-approved uses and are prescribed off-label for longevity. NAD+, glutathione and sermorelin are compounded with no FDA-approved use; compounded drugs are not reviewed by the FDA for safety or effectiveness.

  • Free consultation with licensed physicians
  • Medications shipped to your door
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Active adults on a longevity protocol
Personalized support
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No hidden fees
LegitScript-certified

Get longevity drugs online

Each medication below is studied for its effects on aging biology. None is FDA-approved to slow aging. Your physician reviews your labs, goals and health history and decides what, if anything, is appropriate. Click any option to learn more, or book a consultation to discuss them.

Rapamycin
Rapamycin (sirolimus)
FDA-approved to help prevent kidney transplant rejection and to treat lymphangioleiomyomatosis (LAM). Some physicians prescribe it off-label in longevity programs; it is not FDA-approved for aging, and no human trials have shown it extends lifespan. Sirolimus labeling carries a boxed warning for immunosuppression, infection and malignancy.
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NAD+
NAD+ (nasal spray and injection)
NAD+ levels decline with age, which is why it is studied in aging research. Available as a compounded nasal spray or injection after a physician review. NAD+ has no FDA-approved use and is not proven to improve energy, focus or aging.
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Glutathione injection
Glutathione injection
An antioxidant the body makes on its own. Glutathione injection is a compounded drug with no FDA-approved use; it is not FDA-approved for detoxification, skin lightening, immune support or aging. Prescribed only after a licensed physician review.
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Sermorelin
Sermorelin
GHRH analog that signals your body's own growth hormone release. Prescribed after provider evaluation. Compounded; not FDA-approved.
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Methylene blue
Methylene blue
FDA-approved only as an IV treatment for acquired methemoglobinemia. Other uses, including energy and cognition, are off-label and not FDA-approved; forms prescribed for these uses are compounded. A physician consultation is required before prescribing.
Note: Methylene blue can cause serious or fatal serotonin syndrome with serotonergic drugs (SSRIs, SNRIs, MAOIs). Physician review is required before prescribing.
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How to get a longevity prescription online

Step 1
Sign up
Create your Heally account in under two minutes. Complete a short health questionnaire so your physician can review your history before the visit.
Step 2
Free virtual consultation
Meet a board-certified longevity doctor online via secure video. Discuss your symptoms, goals, and any labs you already have. Your physician explains what options make sense for you and why.
Step 3
Get your prescription
If a protocol is appropriate, your longevity medication prescription goes to a licensed pharmacy. Medications ship to your door within 5 to 7 business days.
Step 4
Ongoing monitoring
Follow-up labs and check-ins are built in. Your physician adjusts your protocol as you respond.
Get started

What to know before starting longevity medicine

Review these points before your visit. Your physician decides what, if anything, is appropriate for you.

Symptoms need a medical evaluation

Fatigue, slower recovery, brain fog, low mood or weight change can have treatable medical causes. These should prompt a medical evaluation, which your physician does first.

FDA status

No medication is FDA-approved to slow aging. Rapamycin, metformin and methylene blue have other FDA-approved uses and are prescribed off-label; NAD+, glutathione and sermorelin are compounded with no FDA-approved use.

How they work

Each option is studied for effects on aging biology, such as mTOR signaling, NAD+ levels or oxidative stress. Most of this evidence comes from laboratory and animal studies and is not proven in humans.

Provider evaluation

Your physician reviews your health history, medications and labs. Some options are not appropriate with certain conditions, medications, pregnancy or breastfeeding.

Side effects and interactions

Each medication has side effects and drug interactions, including infection risk with rapamycin and serotonin syndrome with methylene blue.

Monitoring

If you start treatment, your physician follows up with check-ins and labs and decides whether to continue, adjust or stop.

Check if longevity medicine is right for you

Book your free anti-aging consultation

Have questions about longevity medications? A licensed Heally physician can review your goals and health history in a free video visit.

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Licensed longevity doctors online at Heally

Licensed physicians who explain the evidence, FDA status and risks of each option, and monitor you if treatment is prescribed.

Dr. Vanessa Niles, M.D.

OB/GYN & Longevity

More than 30 years in Obstetrics and Gynecology, with specialized experience in hormone therapy, metabolic wellness, and longevity medicine. Medical reviewer for Heally's longevity content, covering rapamycin, metformin, NAD+, sermorelin, glutathione, and methylene blue.

  • M.D., R.N., F.A.C.O.G., Meharry Medical College
  • 30+ years of clinical experience
4.9average patient rating

Dr. Benjamin Krasne, M.D.

Hormone Optimization

Board-certified anesthesiologist with extensive experience in hormone optimization and telemedicine. Provides anti-aging treatment online across the United States.

  • M.D., University of Miami School of Medicine
  • Board-certified anesthesiologist
4.8average patient rating

Why patients choose Heally for longevity care online

100% online, no clinic visits
Consultations, prescriptions, and follow-ups all happen from home. Available in all 50 states. No more searching for a longevity doctor near me.
Board-certified physicians
Licensed physicians who explain the evidence, FDA status and risks of each option.
Several options discussed in one place
Rapamycin, NAD+, glutathione, sermorelin, methylene blue and metformin can be discussed with one coordinating physician, who decides what, if anything, is appropriate.
Transparent pricing
Consultation is free. Medication pricing is shown upfront. No hidden fees and no membership required.
Ongoing monitoring
Your physician checks in, reviews labs, and decides whether to continue, adjust or stop treatment.
Claim free consultation

How longevity medicine works: targeting the biology of aging

Researchers study aging through several biological pathways, including mTOR signaling, NAD+ levels, oxidative stress, metabolism and hormones. The medications below are studied for effects on these pathways; none is proven to slow aging in humans or FDA-approved for aging.

mTOR inhibition (rapamycin)

mTOR regulates cell growth. Rapamycin inhibits mTOR and is studied for effects on aging; it extended lifespan in some animal studies but is not proven to slow aging in humans.

AMPK activation (metformin)

AMPK is the cell's energy sensor. Metformin, FDA-approved for type 2 diabetes, is studied for effects on aging; it is not proven to slow aging in humans.

NAD+ restoration (NAD+ spray and injection)

NAD+ is a coenzyme used by sirtuins, proteins involved in DNA repair and metabolism. NAD+ is studied for effects on aging; it is not proven to slow aging in humans.

Growth hormone support (sermorelin)

Sermorelin is a GHRH analog that signals the body's own growth hormone release. It is studied for effects on aging; it is not proven to slow aging in humans and is compounded and not FDA-approved.

Antioxidant defense (glutathione injection)

Glutathione is an antioxidant the body makes on its own. It is studied for effects on oxidative stress; injected glutathione is not proven to slow aging in humans.

Mitochondrial support (methylene blue)

In laboratory studies, methylene blue acts as an electron carrier in mitochondria. It is studied for effects on aging; it is not proven to slow aging in humans.

Not sure where to start?

Book a free consultation. Your Heally physician will review your labs, symptoms, and goals. Your physician decides what, if anything, to prescribe.

Book free consultation

Are longevity medications safe?

Rapamycin, metformin and methylene blue have known safety profiles for their FDA-approved uses; their safety for longevity use has not been established. NAD+, glutathione and sermorelin are compounded, and compounded drugs are not FDA-approved and are not reviewed by the FDA for safety or effectiveness.

That said, longevity medications are not supplements. Each has real pharmacological activity and potential interactions. This is why Heally requires a physician consultation before prescribing any protocol.

Side effects and warnings to know

  • Rapamycin: mouth sores, higher risk of infection, raised cholesterol, triglycerides and blood sugar, slower wound healing; boxed warning for immunosuppression, infection and malignancy
  • Metformin: gastrointestinal discomfort; boxed warning for lactic acidosis, a rare but serious risk
  • NAD+: flushing, nausea or headache
  • Glutathione injection: injection-site discomfort, rash or allergic reaction
  • Sermorelin: injection-site reactions, water retention at higher doses
  • Methylene blue: blue-green coloring of urine; can cause serious or fatal serotonin syndrome with SSRIs, SNRIs, MAOIs and some other medications

Your Heally physician monitors your response through regular check-ins and lab reviews and adjusts dosing if needed.

FAQ about longevity medicine

When should I start longevity medicine?
There is no established age to start, because no medication is FDA-approved to slow aging. A licensed physician can review your health history and explain the evidence, FDA status and risks of each option.
How do longevity drugs work?
These are prescription medications studied for their effects on aging biology; none is FDA-approved for aging. Each is studied for a specific pathway: mTOR (rapamycin), AMPK and metabolism (metformin), cellular energy (NAD+), growth hormone signaling (sermorelin), oxidative stress (glutathione), or mitochondrial function (methylene blue). These effects are not proven to slow aging in humans.
How do I get a longevity prescription online?
Book a free consultation with a Heally longevity physician. They review your health history and any labs and explain the FDA status and risks of each option. If a prescription is appropriate, it goes to a licensed pharmacy for home delivery.
What is the difference between lifespan and healthspan?
Lifespan is how long you live. Healthspan is how long you live well. Longevity programs focus on healthspan, but no medication is FDA-approved to extend lifespan or healthspan.
Do I need lab work to start?
Basic labs are recommended before starting most longevity medications. Your Heally physician will tell you exactly which tests are relevant and can order them if you do not already have recent results.
Will insurance cover longevity medications?
Most longevity medications are used off-label and are not covered by insurance for that use. Heally offers transparent self-pay pricing with no hidden fees. Metformin may be covered if you have a type 2 diabetes diagnosis.
Is longevity medicine the same as anti-aging treatment?
The terms overlap. Anti-aging treatment covers a broad range of approaches including cosmetic procedures and topical products. Longevity medicine refers to prescription medications studied for their effects on aging biology; none is FDA-approved for aging.
Can women use longevity medications?
Yes, these medications can be prescribed to women and men when a physician decides they are appropriate. Some are not appropriate during pregnancy or breastfeeding, and your physician will factor in hormonal status and reproductive health.

Start your longevity consultation today

Book a free consultation with a Heally longevity physician. Discuss your goals, review your labs, and find out whether any option is appropriate for you. All online, all from home.

Schedule free consultation

Over 8,000 patients treated. Licensed physicians. LegitScript-certified. Medications dispensed through licensed compounding pharmacies.

Dr. Niles
Reviewed by Dr. Niles, M.D., R.N., F.A.C.O.G.

This page was reviewed by Dr. Niles. With more than 30 years of experience in Obstetrics and Gynecology and deep expertise in hormone health, metabolic wellness, and longevity medicine, Dr. Niles reviews Heally's longevity content to ensure accuracy and clinical relevance across all protocols. Last updated 10/05/2026.

This page is for general educational purposes only and is not medical advice. Longevity medications are prescription treatments used under the supervision of a licensed physician. No medication is FDA-approved to slow aging. FDA status: rapamycin (sirolimus) is FDA-approved to help prevent kidney transplant rejection and to treat LAM, and is off-label for longevity; metformin is FDA-approved for type 2 diabetes and is off-label for aging; methylene blue is FDA-approved as an IV treatment for acquired methemoglobinemia, and other uses are off-label; NAD+, glutathione and sermorelin are compounded and have no FDA-approved use. Compounded drugs are not FDA-approved and are not reviewed by the FDA for safety or effectiveness. Off-label longevity use is not covered by insurance. Each has real pharmacological activity and potential interactions, which is why a physician consultation is required before prescribing. Individual results vary. Always consult a licensed healthcare provider before starting any treatment.