Longevity 101
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What are Free Radicals?

Free radicals are unstable molecules that can cause cellular damage, contributing to aging and various diseases. The body produces free radicals as a byproduct of normal metabolic processes and environmental exposures. The accumulation of free radicals over time leads to oxidative stress, underscoring the importance of strategies to neutralize these molecules and mitigate their damaging effects as part of longevity interventions.

Free radicals are unstable atoms that can damage cells, causing illness and accelerating aging. These molecules have an unpaired electron, making them highly reactive with other molecules in the body. The damage they cause to cells, known as oxidative stress, is linked to a range of chronic diseases including cancer, arthritis, cardiovascular diseases, and neurological disorders. Aging is characterized by an increased production of free radicals and a decrease in antioxidative defenses, highlighting the importance of managing oxidative stress.

Antioxidants are critical in combating the negative effects of free radicals by neutralizing them and preventing their harmful cell interactions. Understanding and controlling free radical production through lifestyle choices and possibly supplementation can significantly influence healthspan and longevity. Research continues to explore the mechanisms of free radicals in aging, aiming to devise strategies that mitigate their detrimental effects while supporting the body's natural defense systems.

Related terms

Oxidative Stress

Oxidative stress, resulting from an imbalance between free radicals and antioxidants, is a significant contributor to the aging process and related diseases. Strategies to reduce oxidative damage, including antioxidant-rich diets and lifestyle changes, are crucial in mitigating aging effects and enhancing longevity.

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Antioxidants

Antioxidants are substances that can prevent or slow damage caused by free radicals, thus playing a crucial role in combating oxidative stress and promoting cellular health. Found in a wide variety of foods, particularly fruits and vegetables, antioxidants like vitamins C and E, flavonoids, and polyphenols, are essential for maintaining health and preventing age-related decline, highlighting their importance in a longevity-focused lifestyle.

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Cellular Senescence

Cellular senescence describes a state in which cells cease to divide but do not die, contributing to aging and age-related disorders. Targeting and removing senescent cells to improve tissue function and delay aging manifestations is a promising strategy in anti-aging medicine, with the potential to enhance health and longevity.

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