What is Spermidine?

Spermidine, a naturally occurring polyamine found in foods like aged cheese, mushrooms, and soybeans, has been linked to cellular autophagy, a process vital for removing damaged cell components and supporting cellular renewal. Studies suggest spermidine supplementation may extend lifespan and improve cardiovascular health by enhancing cellular function and reducing inflammation, positioning it as a promising compound in longevity research.

Spermidine is a naturally occurring polyamine that has been associated with cellular processes like growth and survival. It is found in various foods like aged cheese, mushrooms, legumes, and whole grains. Spermidine promotes autophagy, a cellular renewal process that is crucial for removing damaged cellular components and maintaining cellular function. This process is linked to various health benefits, including enhanced longevity and reduced risk of disease.

Studies on spermidine suggest that its regular intake might help extend lifespan by improving cellular resilience and overall health. The mechanism involves not only autophagy but also protection against oxidative stress and stabilization of genetic information within cells. Additionally, spermidine has been shown to improve cardiovascular health by reducing hypertension and preventing arterial stiffness, making it a compound of high interest in anti-aging research. Its potential to mimic the effects of calorie restriction, a known lifespan-extending strategy, further underscores its relevance in studies focused on extending healthspan.