What is NAD+ (Nicotinamide Adenine Dinucleotide)?

NAD+ is vital for energy metabolism, DNA repair, and cell survival, but its levels decline with age. Boosting NAD+ through supplementation or other means could reverse aspects of aging and improve cellular function, making it a key target in the quest for increased longevity and better health in later years.

NAD+ is a molecule found in every cell of the body and plays a critical role in generating energy and maintaining cellular health. As we age, levels of NAD+ naturally decline, which is linked to aging and many chronic diseases. This decline in NAD+ impairs the function of mitochondria, the powerhouses of the cells, leading to decreased energy production and increased vulnerability to stress and damage.

Research into boosting NAD+ levels is a promising area in the field of aging. Increasing NAD+ can potentially reverse some aspects of aging and improve metabolic functions, mimicking the effects of calorie restriction—a known strategy for extending lifespan. Supplements that boost NAD+, such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), are currently being studied for their potential to enhance healthspan and treat age-related diseases by restoring cellular energy levels.