What to expect in your first month on Wegovy

Starting a new medication can be both exciting and nerve-wracking. If you’ve been prescribed Wegovy (semaglutide) for weight management, knowing what to expect during your first month can help you navigate the experience with confidence. This guide will walk you through the initial weeks of treatment, from your Wegovy first dose to the changes you might experience as your body adjusts.

How Wegovy Works in the First Weeks

Wegovy works by mimicking a hormone called GLP-1 that regulates appetite and digestion. During your first month on Wegovy, the medication begins influencing several body systems by sending signals of fullness to your brain more quickly, slowing digestion to keep you satisfied longer, and improving blood sugar regulation which can reduce carbohydrate cravings.

Wegovy follows a gradual dose escalation schedule to minimize side effects. You’ll start with the lowest dose (0.25 mg) for the first four weeks. This isn’t considered a therapeutic dose for weight loss but serves as an introduction period for your body to adjust. This gradual approach is why many people don’t see significant weight loss during the first month—your body is primarily adapting to the medication rather than responding fully to its weight loss effects.

Common Side Effects During the First Month

Understanding potential Wegovy week 1 side effects and beyond can help you prepare and manage them effectively. Nausea is perhaps the most common side effect, especially during the first week. It typically peaks 1-2 days after injection and gradually improves. For many, this symptom becomes less intense as the body adjusts to the medication over subsequent weeks.

Digestive changes including diarrhea or constipation may occur as your digestive system slows down. Fatigue or low energy can happen during the adjustment period. Headaches or mild dizziness are occasionally reported, often related to dehydration or changes in eating patterns. Injection site reactions such as redness or swelling may occur but are typically mild and temporary.

These side effects are generally most noticeable during the first 1-2 weeks and tend to improve as your body adjusts. By weeks 3-4, many people report significant improvement in most initial side effects.

Tips to Make Your First Month on Wegovy Easier

Successfully navigating the Wegovy week by week experience involves some practical strategies. Stay well-hydrated by drinking plenty of water throughout the day to help minimize headaches, nausea, and constipation. Adjust your eating patterns by having smaller, more frequent meals rather than three large ones to reduce digestive discomfort.

Modify your diet to include more protein and fiber while reducing fatty, spicy, or highly processed foods. Take your injection consistently on the same day each week, ideally in the morning. Track your experience in a journal, noting side effects, hunger levels, and energy. Plan restful activities for the day after your injection, when side effects might be most noticeable.

What Results Can You Expect in Your First Month?

When starting Wegovy, it’s important to set realistic expectations. Weight loss during the first month is typically modest, with most people losing about 1-4 pounds. This varies significantly between individuals based on starting weight, metabolism, diet, and activity level.

Appetite changes often become noticeable before significant weight loss, with many people reporting reduced hunger within the first two weeks. Energy levels may initially dip but often begin to stabilize toward the end of the first month. The most significant changes typically begin after the first month, once you move to higher doses.

When to Talk to a Doctor or Get Support

During your first month on Wegovy, certain situations warrant reaching out to your healthcare provider. Contact your doctor if you experience severe or persistent side effects that significantly impact your daily functioning or don’t improve after the first two weeks. Difficulty tolerating the starting dose might indicate that you need a more gradual approach or additional support.

Questions about food choices, meal planning, or managing side effects are appropriate to discuss with your healthcare team. Mental health concerns like increased anxiety or mood changes should be addressed promptly. Remember that your treatment journey is unique, and regular communication with your healthcare team will help ensure your experience is as positive and effective as possible. Schedule a consultation with Heally today if you need additional support or have concerns about your Wegovy treatment.